Girls With Balls is the story of a women's volleyball team which, after playing the final match of the season and becoming league champions, leave the court and go directly to their motor home to start the trip that they all had planned. On their journey, they stay away from cities and get into the hills on roads surrounded by woodlands. They get lost and end up reaching the only place where, apparently, there is anybody. In this abandoned house, they find a strange group of hunters. This sets up the great hunt, a bloody chase with the girls escaping from their sinister pursuers.